Both consequences can even appear in asymptomatic patients 4. Severe COVID-19 is less common in children than in adults 3 however, at least two long-term consequences occur following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children: multisystem inflammatory syndrome (MIS-C) and long-COVID. However, many individuals experience debilitating COVID-19 symptoms months later, requiring additional medical attention and follow-up. Until now, the focus was primarily aimed at the acute phase of the disease. Still, treatments have been developed during this time, and effective vaccines have been widely administered to the population, both children and adults, protecting millions from severe disease and death 2. Consequently, millions of cases and thousands of deaths have been reported worldwide 1. It has been over 2 years since the coronavirus disease 2019 (COVID-19) pandemic was first declared. Limitations of the studies analyzed include lack of standardized definitions, recall, selection, misclassification, nonresponse and/or loss of follow-up, and a high level of heterogeneity. Children infected by SARS-CoV-2 had a higher risk of persistent dyspnea, anosmia/ageusia, and/or fever compared to controls. The literature search yielded 8373 publications, of which 21 studies met the inclusion criteria, and a total of 80,071 children and adolescents were included. The prevalence of long-COVID was 25.24%, and the most prevalent clinical manifestations were mood symptoms (16.50%), fatigue (9.66%), and sleep disorders (8.42%). The Preferred Reporting Items for Systematic Reviewers and Meta-analysis (PRISMA) reporting guideline was followed (registration PROSPERO CRD42021275408). Heterogeneity was assessed using I 2 statistics. Random-effects meta-analyses were performed using the MetaXL software to estimate the pooled prevalence with a 95% confidence interval (CI). We have used PubMed and Embase to identify observational studies published before February 10th, 2022 that included a minimum of 30 patients with ages ranging from 0 to 18 years that met the National Institute for Healthcare Excellence (NICE) definition of long-COVID, which consists of both ongoing (4 to 12 weeks) and post-COVID-19 (≥ 12 weeks) symptoms. The message to parents, she said, should be one of reassurance.The objective of this systematic review and meta-analyses is to estimate the prevalence of long-COVID in children and adolescents and to present the full spectrum of symptoms present after acute COVID-19. Roberta DeBiasi, chief of infectious diseases at Children’s National Hospital in Washington. The study's estimates of about 5% to 10% of kids with long Covid line up with what pediatric infectious disease experts are seeing in their clinics, said Dr. That’s an increase from 68,000 reported cases the week before. More than 75,000 new pediatric cases were reported the week ending July 14, according to the American Academy of Pediatrics. The number of children testing positive for Covid has been rising in recent months. Nearly 1 in 10, or 9.8%, of children who were sick enough with Covid to be admitted to the hospital reported ongoing symptoms - often fatigue, cough and shortness of breath - three months later.Īmong Covid-positive kids sent home directly from the ER, 4.6% continued to have symptoms 90 days later, the report found. The project included 1,884 children diagnosed with Covid and seen in an emergency department from March 2020 through late January 2021, as well as 1,701 children without Covid, but who sought urgent care for other reasons.
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